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About iTIVA pro Anesthesia

"Manage any volumetric pump like a TCI device with different intravenous drugs"

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iTIVA is a simulation program that provides information about distribution of drugs based on mathematical models, and it simulate the behavior of a TCI pump, obtaining infusion rates to reach and maintain a stable target effect site concentration, those schemes can be implemented in volumetric infusion pumps, and be guided with pharmacokinetics models.
So now pharmacokinetics can become an easy topic and understanding what is going on during a infusion of a intravenous drug, too.

Pharmacokinetic models

iTIVA has 11 drugs y 33 pharmacokinetic models, that are updated continuously:

Adults: Minto
, Eleveld, Kim
Kids: Rigby-Jones, Ross


Adults: Shafer, Scott

Kids: Ginsberg, Encinas (Neonates)


Adults: Gepts, Bovill

Kids: Greely


Adults: Maitre

Adults: Domino, Clements-250

 Kids: Herd, Elkomy

Adults: Seifen


Adults: Dyck, Schnider


Adults: Schnider, Eleveld, Marsh, Cortinez

 Kids: Peadfusor, Kataria, Eleveld


 Adults: Hannivoort, Dyck, Lin, Venn

Kids: Potts


Adults: Albrecht, Greenblatt


Adults: Grassin-Delyle
Kids: Goobie, Grassun-Delyle

iTIVA also calculate the end tidal (Et) for Isoflurane, Sevoflurane, Desflurane for the MAC age, with the use of the Mapleson equation.

Created by David Ramirez MD, Cali - Colombia. Universidad de Valle. [email protected]


iTIVA is not designed to handle intravenous drugs for individual patients. Its use is limited to educational purposes to demonstrate pharmacokinetic principles when performing intravenous anesthesia. Therefore the user assumes all risks from the use of this application for clinical purposes.
Infusion schemes are obtained from concentrations based on models published in the medical literature; therefore concentrations achieved from these schemes can vary widely, in the same manner for clinical effects.
This application should only be used by people with extensive knowledge in Anesthesiology.

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"Manage any volumetric pump like a TCI device with different intravenous drugs"TRY...

Abdul Hameed
Great for doing paediatric TCI .
Daniel Shmukler
frankie so