KINRAKU

KINRAKU is a visual-first educational app for microbiology, infection dynamics, and evolution. The 13th installment in the SUUGAKU / BUTURAKU / DENRAKU / HARAKU / NETURAKU / SEIRAKU / KORAKU / RYORAKU / RYURAKU / KAKURAKU / KIKARAKU / KAGAKU series. This time the theme is "microbes, infection, and evolution." Twelve core topics from high-school to introductory-university biology, all delivered through beautiful simulations and hands-on interaction. [12 Features] - Microbe Atlas 17 species across Bacteria, Archaea, Eukarya, and Viruses. Tap any card for shape, size, habitat, and role. - Cell Structure Cross-sections of all three domains. Bacterial nucleoid, plasmids, and flagellum; archaeal S-layer and ether-linked membrane; eukaryotic nucleus, mitochondria, ER, and vacuole — all labeled. - Cell Division Binary fission, budding, and sporulation animated through one full cycle. Watch N(t) = N₀ · 2^(t/g) climb as you tune the generation time. - Petri Dish Tap to inoculate three different microbes. Adjust nutrient, temperature, and pH to see colony growth shift and species compete where they meet. - Biofilm Planktonic cells attach to a surface and secrete an EPS matrix to build a 3D community. Watch the four stages — attachment, microcolony, maturation, dispersal — plus quorum-sensing switching and the high drug resistance inside the matrix. Tune attachment and growth rates. - Chemotaxis Bacteria swim toward nutrients (attractants) and away from toxins (repellents) via run-and-tumble. Move the source with a tap or drag and watch the population climb the gradient and aggregate. Tune cell count, sensitivity, and swim speed. - Fermentation Switch between lactic acid bacteria, yeast, and koji mold. Watch the substrate fall and products (lactate / ethanol / CO₂ / enzymes) accumulate, with live pH readout. - SIR Simulator 180 agents wander and infect each other. Real-time epidemic curve, live S/I/R/V counts, and the basic reproduction number R₀. Sliders for β, γ, mobility, and vaccination dramatically reshape outbreaks. - World Map Metapopulation SIR over 7 Japanese regions, coupled by travel. Press lockdown to halt cross-region transmission; apply vaccination and observe herd-immunity effects. - Immune System Macrophages follow chemotactic gradients, chase pathogens, and engulf them. Tilt the balance between immune count and pathogen growth and watch infection establish or clear. - Resistance Evolution Three sliders: antibiotic concentration, mutation rate, growth rate. Apply pressure and watch susceptible cells die while rare resistant mutants take over — the resistance histogram shifts right as evolution unfolds. - Tree of Life The full tree from LUCA to the three domains and major clades. Pinch to zoom across billions of years of evolution. [Highlights] - Formula reference sheet on every screen - Live dynamics for SIR, logistic growth, and selection - Japanese / English support - Dark mode / Light mode - Clean, intuitive UI - Only a small banner ad at the bottom [Recommended for] - High-school biology and university microbiology / public-health students - Anyone wanting to intuitively grasp epidemic models and antibiotic resistance - Teachers looking for interactive teaching materials - Anyone curious about how life evolved at the microscopic scale